Basic Information
VIS ID
TVIS10019986
Fusion event
HBV-chr22:q13.2 integration
Validated
No
Detection method
RNA-Seq
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2013
PubMed ID
24085110
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Host Sequence
Chromosome
chr22
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
41393086/40997082 (Hg38)
End
41393239/40997235 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA22A
Nearest miRNA
hsa-mir-1286/Upstream/183124; hsa-let-7a-3/Downstream/95278;
Nearest TSS
ENST00000624155/Upstream/30881; ENST00000637592/Downstream/94551;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/45327, chr22-CpG: 111/Downstream/24442
Upstream sequence
attcttctgcctcagcctccctagtagctgggattacaggcatgcgccaccacacccagctagttttttatatttttagtagagacactgtttcaccatg
Downstream sequence
tatgaaaccatttttatctttgccaatcattaagtgtaaatggaatctcattgtggatttaagtgaaattgagcatccctttatttaagagccataataa
Target sequence
ccaggcaggtctcgaactcctcacctcagttgatccacccgcctcggcctcccaaagtgctgggattacaagcgtgagccaccgcccccggccAGATTTGTTTTTATCTAGATCAGAACTGTCCAACAAAAATAGAATACAAGCCATCTAtat
Reference
Tang, K. W., et al.The landscape of viral expression and host gene fusion and adaptation in human cancer. Nat Commun,2013, 4: 2513.
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