Basic Information
VIS ID
TVIS10020122
Fusion event
HBV-chr2 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1052
End
2148
Orient
+
Integrated sequence
GATGCCTTTATATGCATGTATACAATCTAAGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATATCTAAACCTTTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCG
Host Sequence
Chromosome
chr2
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
36286191/36059048 (Hg38)
End
36287239/36060096 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-1301/Upstream/587562; hsa-mir-10b/Downstream/11317579;
Nearest TSS
ENST00000437798/Upstream/896245; ENST00000428774/Downstream/295018;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/2331431, chr2-CpG: 191/Downstream/295158
Upstream sequence
TTTAAAAGTCATCCTTGTGAATTTTGGACAGCTGACTTCTTATAAAGAGCTTCCCTCCTACGCGTTGGGCCTAAAGCCCAGTCCCTGGGACAGCACTCAT
Downstream sequence
TGGCCCTTTAATCATTCAGTATAAATTCCTCCAGGgccaagcaccatctctggcactggggaagcaacaacgaacaaaaaaggatagccccacactcctg
Target sequence
TCTCTGCATATGCCTATGTCTCACACAGTCAGCTCAGCATATGTGACCATCTCAGTCCTCAGCCTGCCTCCCAGGTAGTTCCCTAAAAGTGTCCCACAGGCAACTCTGGCCTCAACTAGTAACAGATTTTGCTAGATTGTTTCACTTCCCAGGGGTGTGATTCAACATGATACATGATCTGACTCATGTAATAGGTCTACAAATTTTTTATTAAAATGTGACTTATGAAACAGTGCAAACATTCAGTATAGATCA
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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