VISDB Viral Integration Site DataBase

VIS ID

TVIS10020127

Fusion event

HBV-CLDN10 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1744

End

2844

Orient

+

Integrated sequence

GGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCCCCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGAGCTTCTGTGGAGTTACTCTCTTTTTTGCCTTCTGACTTCTTTCCTTCTATTCGAGATCTCCTCGACACC

Chromosome

chr13

Cytoband

q32.1

Reference genome

Start

End

96229994/95577740 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-331-3p ; hsa-mir-6810-3p ; hsa-mir-6801-3p ; hsa-mir-6729-3p ; hsa-mir-4756-3p ; hsa-mir-3919 ; hsa-mir-3925-5p ; hsa-mir-486-5p

Nearest miRNA

hsa-mir-1297/Upstream/3086470; hsa-mir-1267/Downstream/849489;

Nearest TSS

Nearest CpG islands

None/Target, chr13-CpG: 551/Upstream/23448, chr13-CpG: 89/Downstream/63612

Upstream sequence

CAACAAAACACCCAGGTATGAAAAAGAGACAAAAATGACCTGTTAAAAAGTAGAATGCTATCATAAATCATTACATGTGGAACAAATTACAGATAGTTCA

Downstream sequence

TGAAAATACTTCTTGGGGCAAGAGGAGAGAAGAAAGCTATCTAAGAAAGAGGAAGATTTACATTTAGATATTGGCAGAGACAGGCCGAAACAGTTTCTTC

Target sequence

TGCCATATGGGAGATCCTTAATAGTAATTTATCACTAAATGATAGCTATTGATTCATTTCCCCACTAGACTGcagcgattagtgacgatttgcacatagcacgtgcttaataaacatttactaaatTGAACTAACATGAAAGCAAAAGCAACCTTTTGTTTTCTAACTAACTACAGTCTGCCTAAATGATTTGCGCTGCAGAACAGAACAAATAGATGGAAAGCTTGGCAAGGTTAAGGCAGCGTGCAGAGGAAA