Basic Information
VIS ID
TVIS10020128
Fusion event
HBV-LOC105375228 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1182
End
2282
Orient
+
Integrated sequence
TTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCG
Host Sequence
Chromosome
chr7
Cytoband
p14.2
Reference genome
GRCh37/hg19
Start
35110808/35071196 (Hg38)
End
35111858/35072246 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA7C
Target gene
LOC105375228
Nearest miRNA
hsa-mir-1183/Upstream/130362; hsa-mir-10399/Downstream/1847111;
Nearest TSS
ENST00000635602/Upstream/32925; ENST00000605778/Downstream/181385;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/33000, chr7-CpG: 97/Downstream/113505
Upstream sequence
TCCTTTTATCATCACTCACCAAAAAACTAGAAAACAGATTCTAATtggaatgctacacagaggtagaaaagagtgaaatcatgtcgtttggagcaacatg
Downstream sequence
TAGTAACCAGCTATTTTGCAGTATAACCTACATTCATTCATGTATTGTTTGTATGAATGTTCTGTTTCCAGCATAATGGCTTTTAAAAATTAAAGATATA
Target sequence
TTCTGTATGTCAGGACCATTTTTCATTACTGCAAAATACTCAAACTAAGTTTTAAAGAAAAGAATTTCTATCCTATGCATTGCTATAAGGCTTTTTATTCCAACATATGGTATTAAATACGAGTTATGTGCTCAACTGTGAATttatatgaaaaggagattaggacacaacaggcatagaggaaagatcatgtgaagacacagggagaaaacacttatctgcaaatcaagaggaaagatcccagaagatactaac
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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