Basic Information
VIS ID
TVIS10020130
Fusion event
HBV-STEAP2-AS1 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1172
End
2272
Orient
+
Integrated sequence
CTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTA
Host Sequence
Chromosome
chr7
Cytoband
q21.13
Reference genome
GRCh37/hg19
Start
89762692/90133378 (Hg38)
End
89763742/90134428 (Hg38)
Orient
-
Location type
Intronic
Target gene
STEAP2-AS1
Nearest miRNA
hsa-mir-10525/Upstream/14218109; hsa-mir-10399/Downstream/2069587;
Nearest TSS
ENST00000635602/Upstream/10488; ENST00000475789/Downstream/19947;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/13656, chr7-CpG: 49/Downstream/19825
Upstream sequence
TGGGTCAAGTGCCTGATTCAAGATGGTGGAAAAACATTCCTTtccattctatagaacacatatgtattggatgtcttttctgtgctgggtatagtgcttg
Downstream sequence
GCATGGGGCATGCACGGCATGAGGCATGAAGAAGAAAGAGATGAGCAATCCTTACCTGAAAAGAGACCACCCTCTCCTTTAATGGGAGGAGAAATTAAAG
Target sequence
TCCATGGCTTTAAGTTTAAAAATAACTTCGCATTTACTAGAGTGGACTTACCCTCCAGGCATAAAATTTTAAAACCCAACAACTCCAGGCCTCCAGAGTCTTTACTTCCCACTAACTTCTCACCAGTGAAGGCGAAGCTAATGAAAAAGGATAGATGACTGCTTCTCAATTGGAAATGGATCCAAATGCCATCAAGGGAATTGGTGTCGGTATACAGATTTTACCTACTGTCACAGCCTGGTTGGGTGGAGGATG
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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