Basic Information
VIS ID
TVIS10020131
Fusion event
HBV-chr7 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1182
End
2282
Orient
+
Integrated sequence
TTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCG
Host Sequence
Chromosome
chr7
Cytoband
p15.3
Reference genome
GRCh37/hg19
Start
22561327/22521708 (Hg38)
End
22562377/22522758 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-1183/Upstream/1050562; hsa-mir-10399/Downstream/3427161;
Nearest TSS
ENST00000635602/Upstream/21210; ENST00000435127/Downstream/40579;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/21305, chr7-CpG: 19/Downstream/26933
Nearby gene
EEF1A1P6(-9658) ;
Upstream sequence
ATAGCTAGTCACCATATTCCTTAGCAAAGGATATTAACAAATGTAGGGCTATGTCTCCTCAGAAGTTTTTAGTAACTTTTCTTTCAGAGGTAAAGCAGGA
Downstream sequence
ACATTATAGTAACCAGCTATTTTGCAGTATAACCTACATTCATTCATGTATTGTTTGTATGAATGTTCTGTTTCCAGCATAATGGCttttaaaaattaaa
Target sequence
AGATGGCATTCTGTATGTCAGGACCATTTTTCATTACTGCAAAATACTCAAACTAAGTTTTAAAGAAAAGAATTTCTATCCTATGCATTGCTATAAGGCTTTTTATTCCAACATATGGTATTAAATAGGAGTTATGTGCTCAATTGTGAATttatatgaaaaggagattaggacacaacaggcatagaggaaaggtcatgtgaagacacagggagaaaacactcatctgcaaatcaagaggaaagatcccagaag
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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