VISDB Viral Integration Site DataBase

VIS ID

TVIS10020134

Fusion event

HBV-CLDN10 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1

End

725

Orient

+

Integrated sequence

TCCACAACATTCCACCAAGCTCTGCTAGATCCCAGAGTGAGGGGCCTATATTTTCCTGCTGGTGGCTCCAGTTCCGGAACAGTAAACCCTGTTCCGACTACTGCCTCACCCATATCGTCAATCTTCTCGAGGACTGGGGACCCTGCACCGAACATGGAGAGCACAACATCAGGATTCCTAGGACCCCTGCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCACAGAGTCTAGACTCG

Chromosome

chr13

Cytoband

q32.1

Reference genome

Start

End

96217253/95564999 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-331-3p ; hsa-mir-6810-3p ; hsa-mir-6801-3p ; hsa-mir-6729-3p ; hsa-mir-4756-3p ; hsa-mir-3919 ; hsa-mir-3925-5p ; hsa-mir-486-5p

Nearest miRNA

hsa-mir-1297/Upstream/3073729; hsa-mir-1267/Downstream/862230;

Nearest TSS

Nearest CpG islands

None/Target, chr13-CpG: 551/Upstream/10707, chr13-CpG: 89/Downstream/76353

Upstream sequence

CACTGTTCATACCTTTGTTTCGTGGCCTTCCCAGGGGAAGTACTGTCTTGTTTATCTTTGCATCTGCTCCTGCTGCGGTCATCGGCAGAGCACTGTCACC

Downstream sequence

GAGCTATGACTATGTTTGATGACTCCAGCATGAGCTCTTGCAGAGCCTTGAAAACTGTTTTTCAACTTTTCCCTTTAGGCTGTGTCAAACTAACTTCCTC

Target sequence

ATATTTTATTTTGGCTTATTCTAGGGATAGCACTTCTCTGGCTAGCATTTGCTGGAATTTGATAATTGATGCTTCTGGTTTTGTTTGTACATGAACTTAGAGAGGAATACGTTGTAGAATCAAAGCTTGTGGCAGGGCCAGTCCTAGATAGGCTGGGATGTGGAAGATGCCACTATAGGAATGTTCTATGTCTTTGGTGTCTTAATCAGCTGGCATAAGAATTAAGTTCCTTGAGGTCAGAAAACGTCTATGCAA