Basic Information
VIS ID
TVIS10020139
Fusion event
HBV-chr9 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1181
End
2281
Orient
+
Integrated sequence
GTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTC
Host Sequence
Chromosome
chr9
Cytoband
q34.11
Reference genome
GRCh37/hg19
Start
132090245/129327966 (Hg38)
End
132091295/129329016 (Hg38)
Orient
+
Nearest miRNA
hsa-let-7a-1/Upstream/935252; hsa-mir-12126/Downstream/540589;
Nearest TSS
ENST00000422679/Upstream/6950; ENST00000427109/Downstream/3284;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/6663, chr9-CpG: 45/Downstream/7828
Nearby gene
C9orf106(-5363) ; LINC01503(+8957) ;
Upstream sequence
tagctcagggtttgtgaatgcaccagtgggcactctgtatccagctaccctggtggggacttggagaacctttatgtctagctgagggattgtaaataca
Downstream sequence
TGTGTTTTAAGACCATGGTTTCATTCCCACTGAGAAATACCCAGCCTTGGTGTTCCGGATGCAGCAACCACGAAGGGGTGGGGGCTCAAGGGTGCAGCCC
Target sequence
gctgtgaatagcatggagCCAGTCCCCACACCAGAGAGCCTTTGAAGGCTTGCTCCACGGAACCAATTGGGAACTGCTGGGCTAAGCCAGTTGGATGGAGGTGCAGTTCTGACCATCCCCGTGGCCACTCCCACTTCCCCTGGACagcagggtatccagggacaactcagtggctgtgggatcaccctgactctgccatttagtaggctgtccttggggagatgacttcccctctctgagaccttgggtcccAGG
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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