Basic Information
VIS ID
TVIS10020140
Fusion event
HBV-LOC105370265 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1165
End
2265
Orient
+
Integrated sequence
CAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCT
Host Sequence
Chromosome
chr13
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
77288787/76714652 (Hg38)
End
77289837/76715702 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA13E
Target gene
LOC105370265
Nearest miRNA
hsa-mir-1297/Upstream/10496328; hsa-mir-1267/Downstream/982310;
Nearest TSS
ENST00000623511/Upstream/700151; ENST00000646457/Downstream/118137;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/1077575, chr13-CpG: 195/Downstream/169485
Upstream sequence
TAGTAGAGGGGATAAAAACTGGGAAGATGAATAAGCTATAAATTGGCTATCAGCACAAAATGAACTGATTTCCTAGCTCTCAAATGTCATCTTTAAAGCA
Downstream sequence
ATTTTACATTAACATCTCTCTTTATCGTGTCTATTCATGACCAGACAGTGAATTTTAAATCAGCTCCTTTTGTAATCCATCTCGAGAAGAATGAAGATGG
Target sequence
CCAAAGAGCCCAATTCTATGTTGTTCCAATCATAATGTTCAAAAAATACCTGCTAAATGTAGATAAAGGCAATGGTTTTGTAAGACTCCTTCAAAGGTGGAATCTACTAGGAGtaaaataaaaataaaatttaaaattacttaaaaataataaattGGCTTACAAATACAAATTAGCATTATTAAGACAACAATATTAAGAATTATATTTTACTGAAGTTTTTTTctgtgataagagttatttcatacatgagtt
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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