Basic Information
VIS ID
TVIS10020142
Fusion event
HBV-chr21 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1150
End
2250
Orient
+
Integrated sequence
TTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCC
Host Sequence
Chromosome
chr21
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
29725062/28352742 (Hg38)
End
29726112/28353792 (Hg38)
Orient
+
Nearest miRNA
hsa-let-7c/Upstream/1398699; hsa-mir-3197/Downstream/2021502;
Nearest TSS
ENST00000624081/Upstream/124075; ENST00000412526/Downstream/185526;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/1208755, chr21-CpG: 29/Downstream/531311
Upstream sequence
AAAATCTCCTCTAACAAAATTAGCCACTCAAATCATCTAAATGAGCTCAACAATGTTATACTAGATTACCTTTCAGAGTAATTAGACCACCCATGCCTGT
Downstream sequence
aatgctagacgacgagttagtgggtgcagcgcaccagcatggcacatgtatacatatgtaactaacctgcacgttgtgcacatgtaccctaaaacttaaa
Target sequence
CAATTTAAGGAGGCTACTTTCTGGAATGTGTTGAACTTGACATCATTCCCAAACTGGTAGAAAATGGAATAATGAGAATTACAGTTTTGATATCTTTTGTTTAGCCAAGTATGCTTTCTTCCACTAAGTGATCATAGCATTTCTTAATATTATAGATACTTCATTTTCTTTGTTCAACCCATTTTGTAACATGCTATGTTACTTTATTATTTTGAAAATTGTAGAATTGTGTCTATTCTTCTTAGGCATATTGGT
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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