Basic Information
VIS ID
TVIS10020144
Fusion event
HBV-chr16 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1175
End
2275
Orient
+
Integrated sequence
CCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGT
Host Sequence
Chromosome
chr16
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
1330407/1280406 (Hg38)
End
1331457/1281456 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-3176/Upstream/510129; hsa-mir-11401/Downstream/453529;
Nearest TSS
ENST00000527434/Upstream/24273; ENST00000562470/Downstream/17710;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/18649, chr16-CpG: 167/Downstream/27272
Nearby gene
TPSP1(-4011) ; TPSP2(+5937) ;
Upstream sequence
TTGACTTCTCTGAGCAGAGTGTCTGCATCTCTTGGAGAGTTACACATTTCTTCATGAGCCATTTTTCTCATTCTTAGATGCACCTGTTTTTATCCTTTGC
Downstream sequence
CCGCCGTAAAGAGGATTTTTGGGAAGAGAAACCACATCGTGAAATTCTCATCATCGTACGTAAGTCCCAGAGGAAAACACTCAGAGCCCCGGCTCTTCAT
Target sequence
CCCTGCACACGGCGTGGCAGCCTTGATGATGGTGACCTGGCCGTGGGCAGTGGGGCCTTTGTGATACATCCTCTCGCAAGCTCGGGTCCTCATGATGGGGACCTCGGCCTCTTGCAGGTCGGGGGCCGGGGGCAGCGGCGCTGTGGGGAGGGACTGGGTGAGCATGGCTGGTCCTGGTGGGCTCAGGCCGTCCGTCCATCTGCCAGGGAGCCTGGGCTGGCAGCCCCTTTTGGGCTCATGGTCCCGCTCAGCAGA
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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