Basic Information
VIS ID
TVIS10020145
Fusion event
HBV-chr5 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1181
End
2281
Orient
+
Integrated sequence
GTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTC
Host Sequence
Chromosome
chr5
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
120380111/121044416 (Hg38)
End
120381161/121045466 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-10397/Upstream/1889700; hsa-mir-103a-1/Downstream/8052222;
Nearest TSS
ENST00000502646/Upstream/263198; ENST00000599562/Downstream/154238;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/580043, chr5-CpG: 71/Downstream/806226
Upstream sequence
TAAAATCCAGAGGACGTGATGTGGCACCAGGCACTGTGGCTCTACCACCGTGAGTGTGGCTCACCCAGTGGCTGTGTGACGGCAGCTCTCCCAGGCCGCC
Downstream sequence
TTCAATACAGAATTATGATGGTGTTATAAGGAATAGAATGGAAGAAGGGTTTAGGGTATCAGTTCTCTTTCACCTTTCTTTTGGCTTATCCAATACTCTA
Target sequence
CTTTGTTAAGAGTTATTCTTGTTAGTAAGACTAAGAGAGTAACTTGATTATGCAAATAAATGTGACAAATTGTACaaataaatattaatttgttataatagttgaaaaaaaattaaaataaaatGGATCCTCAAGAAATCTCAAATCTTGACACCAGGCAATTAGCACTGATGACTATTAAAAAGTAATGTTTGCAAACCATTTGTTGGTTAGTAAATACTTTCTCCTGTAATAATTGAGTTTATTAAAAACCTG
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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