VISDB Viral Integration Site DataBase

VIS ID

TVIS10020147

Fusion event

HBV-FN1 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1090

End

2190

Orient

+

Integrated sequence

TCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATATCTAAACCTTTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTG

Chromosome

chr2

Cytoband

q35

Reference genome

Start

End

216252826/215388103 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-200c-3p ; hsa-mir-200b-3p ; hsa-mir-1-3p ; hsa-let-7g-5p ; hsa-mir-26b-5p ; hsa-mir-615-3p ; hsa-mir-218-5p ; hsa-mir-140-3p

Nearest miRNA

hsa-mir-10b/Upstream/1628894; hsa-mir-1244-1/Downstream/2512410;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/74644, chr2-CpG: 43/Downstream/47441

Upstream sequence

TGATTCCTTATTATGGTTGGGGATAGTCAGTAAAATAGTAGATTCCGTTTTGAGAGCAGTATCAGTGCTCTGGGGCCTGTGAAGGGAGCTTTGGGTGTGC

Downstream sequence

ACCATGACAACAAAAAATGGAGATGTATTTTTAGAAGTAGCATTTCATTTGTTATACAGAATTGATAGGCAAAAGCTACTGGATAGTCATACTGCCAACA

Target sequence

CAACATTTCGTTCCTGTCTCATCAATACCATGATTTGCCATAAACCAAAGAGTAAGATGTACTGATTCTAAGCTACATATGAATTTTAAAATCTTAAATTGACTCAATTCAAAATAGCCAGCTCAAGCATTCATTTTTTTCTTGTGCTAAGTAATTCAAGCAGATTTTAGGGGTTATTACAGTAAGTTTCTGTGTCACATTTGGAGATAAGTGTTCAAGATCTTCTGAGAATTGACATTTTCAAATTCTTCAGTG