Basic Information
VIS ID
TVIS10020158
Fusion event
HBV-chr3 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1164
End
2260
Orient
+
Integrated sequence
TCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCC
Host Sequence
Chromosome
chr3
Cytoband
p21.31
Reference genome
GRCh37/hg19
Start
46316744/46275253 (Hg38)
End
46317792/46276301 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-12127/Upstream/1413272; hsa-let-7g/Downstream/1573254;
Nearest TSS
ENST00000440867/Upstream/10125; ENST00000421659/Downstream/77433;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/279272, chr3-CpG: 26/Downstream/188370
Nearby gene
CCR3(-8547) ;
Upstream sequence
ggagcttaaatgggctgtaccttgtagcattccgaggacaggcctgaattctgagaagggaaagtgataaaagtattgtccagtcctttttggtggctga
Downstream sequence
tccatcctgggtgatagagcaaaaccctgtctcaaaaaaaaaaGATACATATAGATATAGATTTAGATATGGACATAAATAAGGATATGGATATGGGCTT
Target sequence
acagacacttctcaaaagaagaaatttatgctgccaacaaacatatgaagaaaagctcatcatcactggtcattagagaaatgcaaatcaaaaccacaataagacaccatctcatgccagttagaatggtgatcattaaaaagtcaggaaacaacacaggctggagaggatgtggagaaataggaatgcttttatgctgttggtaggagtgtaaattagttcaaccattgtggaagacagtgtggcgattcctca
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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