VISDB Viral Integration Site DataBase

VIS ID

TVIS10020159

Fusion event

HBV-SNX9 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1163

End

2259

Orient

+

Integrated sequence

GTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTC

Chromosome

chr6

Cytoband

q25.3

Reference genome

Start

End

158237198/157816166 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-193b-3p ; hsa-mir-335-5p ; hsa-mir-124-3p ; hsa-mir-196b-5p ; hsa-mir-92a-3p ; hsa-mir-93-5p ; hsa-mir-4258 ; hsa-mir-4519 ; hsa-mir-7156-3p ; hsa-mir-8077 ; hsa-mir-7160-5p ; hsa-mir-4663 ; hsa-mir-6886-3p ; hsa-mir-3188 ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-2467-5p ; hsa-mir-3975 ; hsa-mir-93-3p ; hsa-mir-1184 ; hsa-mir-4649-3p ; hsa-mir-4264 ; hsa-mir-4797-3p ; hsa-mir-5088-3p ; hsa-mir-1910-5p ; hsa-mir-455-3p ; hsa-mir-129-2-3p ; hsa-mir-129-1-3p ; hsa-mir-6757-3p ; hsa-mir-335-3p ; hsa-mir-5096 ; hsa-mir-3152-5p ; hsa-mir-4774-3p ; hsa-mir-6836-3p ; hsa-mir-3679-3p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-136-5p ; hsa-mir-6866-3p ; hsa-mir-188-5p

Nearest miRNA

hsa-mir-10398/Upstream/285918; hsa-mir-1913/Downstream/793541;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/142070, chr6-CpG: 171/Downstream/6403

Upstream sequence

TGCCAAATATGAGCTGGCTCTACTCCTCCTCCAGTTCCTTAAATTCTCTCATGTGTCTTTTAGACTCCATTATATTCCTATCATTTCTACTTCTCACACT

Downstream sequence

aaaccgcccctttgctatgcaaatattgacacgggaggtaacgggtagatcataactatttataagaaccatctgtgtttctaaacagtcatttacttaa

Target sequence

TCTCCCAGTGGTTCTCGTCACCACAATAGAAGAGTTTTGTTTTCAGGAAGGAGCAGAGGACACTAAGTAAGAGTGAAGAGCCAGCCAGGGCTGTCTGTGGGttttttttttttagacagcgtatcactctgttgcccagactggagtgcagtggcctgatcttggctcactgcagcctcggattcctgggctcaagcaatcctcccacctcccacctcagcctcccaagtggctgggactccaggcacatgccac