Basic Information
VIS ID
TVIS10020160
Fusion event
HBV-chr12 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1163
End
2259
Orient
+
Integrated sequence
GTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTC
Host Sequence
Chromosome
chr12
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
108260027/107866250 (Hg38)
End
108261075/107867298 (Hg38)
Orient
+
Nearest miRNA
hsa-let-7i/Upstream/3274534; hsa-mir-1178/Downstream/768512;
Nearest TSS
ENST00000382841/Upstream/1688; ENST00000546811/Downstream/262173;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/21306, chr12-CpG: 40/Downstream/36351
Upstream sequence
CACATGAGGGCACACCTTCAAATTAAACAAATGAAATTTCaagaaaggacagagataatgaagaagacaaaattgtcgaagaaataataaaatatttaaa
Downstream sequence
atcaagctggttgacatatccatcaccttacatacatatcattattttggtgtggtgagaacatttaaaaatctattctcttagcaattttcaagtatat
Target sequence
agaatgggagaaaaattttgcaatctatccatctgataaaaggctaatatccagaatctacgaagaacttaaagaaatgtacaagaaaaaaacaaccccatcaaaaagtgggcaaaggatatgaacagacacttctcaaaagaagacatttatgcagccaacaaacatatgaaataaagctcatcatcactgctcactagagaaatgcaaattaaaaccacaacaatgagataccatgccagttagaatggcgat
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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