Basic Information
VIS ID
TVIS10020161
Fusion event
HBV-chr6 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1163
End
2259
Orient
+
Integrated sequence
GTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTC
Host Sequence
Chromosome
chr6
Cytoband
q16.1
Reference genome
GRCh37/hg19
Start
97007347/96559471 (Hg38)
End
97008395/96560519 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-10398/Upstream/5037734; hsa-mir-1202/Downstream/1464012;
Nearest TSS
ENST00000381078/Upstream/37663; ENST00000450218/Downstream/2029;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/37247, chr6-CpG: 83/Downstream/276435
Nearby gene
UFL1(-4195) ; FHL5(+3054) ;
Nearest cancer related gene
UFL1(TSG, -4195) ;
Upstream sequence
catctgcagttttactttctgcaattgcagttacccacagtcaaccacaatattaaatggaaaattccagaaataaataattcataattttaaattctcc
Downstream sequence
acaaagaagagtctaaacaaacaggccttgctaagttcccccgagtgtataatcattagactatatcccctttgtccagtcatacttttccatgactatc
Target sequence
CCTAAGACAAAAGTCTCAAAGGTTGTCTCATGTTTTGTGTTACTCAATGTAAAGAAGTAAAAGTGCTTTGTCAAACTGTTTTACTACTGAGCCTGTCTTTACTCATCTAAAATGCAGTCCTTAACCTAATTCTATCATACAGACTTCAGAGTTGGGTAAGAACTTGAAGACTTGACACATAGAACATATTGTTGTTTAAATACAACCTAATAAATGTAAATGTACTTAAAGTCAATGTTCTAGATTTTTCTCCTT
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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