Basic Information
VIS ID
TVIS10020162
Fusion event
HBV-C8orf37-AS1 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1163
End
2259
Orient
+
Integrated sequence
GTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTC
Host Sequence
Chromosome
chr8
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
96511820/95499592 (Hg38)
End
96512868/95500640 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA8B
Target gene
C8orf37-AS1
Nearest miRNA
hsa-mir-12123/Upstream/426596; hsa-mir-10400/Downstream/2893005;
Nearest TSS
ENST00000518652/Upstream/66955; ENST00000519366/Downstream/4766;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/230073, chr8-CpG: 118/Downstream/643895
Upstream sequence
tgaaataattatacgactcatcttaatgtagaatcagggggagccctgagcttgtgttcctgaagtcccatttgggagtgatgggagacagtgacagatc
Downstream sequence
gacttacaggctgcaaagtataaaactgatgaaagcaatcaaagaatgtctaaataagtggagagatagtccttgttcatggactggaataccttccata
Target sequence
aagtgagaaaaagaattaaaaggcacacagattggaaaagaagaaataatgctgtacccttgcagatgtgattgtttgtgaagaatccaaaggaaggtctaccaaaaaactagacctaagtttagcaaggttgtaggatacagaagacatttatgcgtccaacaaacatatgaaaaaaagctcattatcactggtcattagagaaatgcaaatcaaaatcacagtgagataccatctcatgccagttagcatggc
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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