Basic Information
VIS ID
TVIS10020165
Fusion event
HBV-chr18 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1163
End
2259
Orient
+
Integrated sequence
GTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTC
Host Sequence
Chromosome
chr18
Cytoband
p11.32
Reference genome
GRCh37/hg19
Start
1843889/1843888 (Hg38)
End
1844937/1844936 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-8078/Upstream/1731549; hsa-mir-1-2/Downstream/2040417;
Nearest TSS
ENST00000575820/Upstream/63559; ENST00000575515/Downstream/61710;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/934315, chr18-CpG: 33/Downstream/726351
Upstream sequence
TTTTTTCTCAACAAATGCCCCTTCTATAAAATTATCCTTTTATGTGAAAATGTATTTTTAATTTCTGAGACTTATTAAGAAAATCCATAAAGACTTTTGC
Downstream sequence
GTATATAttttaaagatgaggtctcactgtgttgcccaggctggtctccaactcctgggctcaagtgatcctcctaccttagcctcccaaagtgctggga
Target sequence
GCGCCAAATGGGTAGGAGGGCATAACTGAATGAATTTCGTACTCCAAGCCTAGTCTTTCGACTAACTTGCCACCAgatttttgtctgtcaggttccctgctgtatacctaacacAATGAATTAGACAAGAATTATCCGACTACTACTCAAATTCCTGGAACATAGTGACTACTCTAAAAATTTATTTTAAAATGTAAAATGTGTATGTAACAATAAAGTAATTTAGAACCCCTCACCCATAAATGGTGTTGTACT
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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