Basic Information
VIS ID
TVIS10020167
Fusion event
HBV-chrX integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1164
End
2260
Orient
+
Integrated sequence
TCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCC
Host Sequence
Chromosome
chrX
Cytoband
q23
Reference genome
GRCh37/hg19
Start
115604401/116473240 (Hg38)
End
115605449/116474288 (Hg38)
Orient
-
Nearest miRNA
hsa-let-7f-2/Upstream/1649676; hsa-mir-105-1/Downstream/1912106;
Nearest TSS
ENST00000429181/Upstream/10237; ENST00000493448/Downstream/219900;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/504176, chrX-CpG: 74/Downstream/1641982
Upstream sequence
ATGGAGATTGTGTGGGAGTCATGGCCACAGTCAAATCATGTTCCATAGGTCCAGTGAGAGTATTGGGTATGCTGTTAAAAACTGGATTCAggccgggcgc
Downstream sequence
gacaggagaattgcttgaacttgggaggcggaggttgcagtgagtcgagatcataccactgcacttcagccttttgacagagagagactgcgtctcaaaa
Target sequence
ttgttgttgttgttgtttttccattcagctactatgtgtcttttgattggagagcttagtccatttacattaaatgttattattggtaggtaaggacttacttccattttgttatttgttttctggtcttctctttgttcttgatttcctttctctcatccttcagcaaaggtgatttgctctggtgatacaatttcgtttctggcttttaaaaaatattcattgtattttgtttggtttgaagttaccataagg
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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