VISDB Viral Integration Site DataBase

VIS ID

TVIS10020170

Fusion event

HBV-SNTG1 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1164

End

2260

Orient

+

Integrated sequence

TCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCC

Chromosome

chr8

Cytoband

q11.21

Reference genome

Start

End

51671717/50759157 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-2681-5p ; hsa-mir-548c-3p ; hsa-mir-7977 ; hsa-mir-23c ; hsa-mir-23b-3p ; hsa-mir-23a-3p ; hsa-mir-130a-5p ; hsa-mir-3671 ; hsa-mir-6849-3p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p

Nearest miRNA

hsa-mir-124-1/Upstream/7861834; hsa-mir-10400/Downstream/10955631;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/847809, chr8-CpG: 98/Downstream/649445

Upstream sequence

AAACTAGCTTCTGCCAGGAAGCCCTTCCCAACTAACTCCAGCTCCTTCTGCATCTTTGTCTTCTGACAGCCACCTTGCACTGTACTTGATGAATTTTCTG

Downstream sequence

ttgtttttttctcataaatttgtttaagttctttgtagattctggatattagtcccttgtcggatggatagattgcaaaaattttcccccattctgtagg

Target sequence

gaatttgcattttctgcatacattgcttatttgttcttgcatgtggtctattttatctattaaagcttgtggtatattaatcatagttgtttcaaatgcttgttctaataaatccagtgtccctgccatatctgcacctggtcatgcttgccctatctctgtaaactgtgatgtcttttttccgtgtattatgatttgcaatattttcttttttaattgtttttattataatttaagttcagagataaatgtgca