PPFIA2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10020171
Fusion event
HBV-PPFIA2 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1163
End
2259
Orient
+
Integrated sequence
GTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTC
Host Sequence
Chromosome
chr12
Cytoband
q21.31
Reference genome
GRCh37/hg19
Start
81875746/81481967 (Hg38)
End
81876794/81483015 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA12B
Target gene
PPFIA2
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-let-7i/Upstream/323506; hsa-mir-1178/Downstream/5262053;
Nearest TSS
ENST00000382841/Upstream/36389; ENST00000550506/Downstream/29330;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/403627, chr12-CpG: 34/Downstream/275526
Upstream sequence
CTACTTTGAAGAATTTGGAGAATTAAGCAAAACATACGAagttctcaattttcctacataatgcattgctgaaaattttcaaattggttaaacttgaaca
Downstream sequence
TTTTATAAATGTGAGATAGAATAATTCTGCCACAACAGCTGTGCATATTAAAAAGTTATGTAGAACCCTACATTAAGCAATtcatcattgctggcagaac
Target sequence
gagaaaatttttgcaatctatccatctgacaaagggctaatatccagaatctacaaagaacttaaacaaattaacaagaaagaaacaaccccatcaaaaagtgggcaaaggacatgaacagacacttctcaaaagaagacatttatgcggccaacaaacatgaaaaaaaaagctcatcatcactgttcattaaagaaatgcacattaaaaccacaatgagataccatctcatgccagttagaatggcaattatta
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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