Basic Information
VIS ID
TVIS10020172
Fusion event
HBV-chrX integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1164
End
2260
Orient
+
Integrated sequence
TCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCC
Host Sequence
Chromosome
chrX
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
73117736/73897901 (Hg38)
End
73118784/73898949 (Hg38)
Orient
-
Nearest miRNA
hsa-let-7f-2/Upstream/3874978; hsa-mir-105-1/Downstream/319428;
Nearest TSS
ENST00000429181/Upstream/45148; ENST00000453317/Downstream/45235;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/334572, chrX-CpG: 41/Downstream/206380
Upstream sequence
AGAGAAGGAATGAAATGCACTAGAGGAACAAACTTGATGCTTTTTCTTTGTTTGGCTTCACCATTATTCATATTACTACTACCACTAGAGACAGTCACTT
Downstream sequence
gcctggccaacatgatgaaaccctgtctctactaaaaatactaaaattagttggacatggtggcgcacctgtaatcctggctatcctgtaggctgaggtg
Target sequence
tataaaatgggagaaaatttttgcaatctatccatctgaaaaaggactaatatctagaatctacaaggaacttaaacaaatttacaagaaaaaaacaaacaaccccatcaaaaagtgagcaaagtatacgaacaaacacttttcaagagaagacatttatgcaaccaacaaacatatgaaaaaaagctcatcatcactggtcattagagaaatgcaaatcaaaaccacaatgagataccatctcacgccagttag
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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