Basic Information
VIS ID
TVIS10020173
Fusion event
HBV-chr8 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1163
End
2259
Orient
+
Integrated sequence
GTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTC
Host Sequence
Chromosome
chr8
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
60212075/59299516 (Hg38)
End
60213123/59300564 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-124-1/Upstream/16403241; hsa-mir-10400/Downstream/2414224;
Nearest TSS
ENST00000518652/Upstream/179570; ENST00000522898/Downstream/293137;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/179329, chr8-CpG: 14/Downstream/873002
Upstream sequence
CAAGTGCCTGCTCTTTGGAGGGCATCTAGTTCAATgtgagcatttttttctacccagcgaccaattctggaaacatcaaagtgtttatgagcctactttt
Downstream sequence
TAAAATCATCACAGTATTTTTGGAAATgaattgactttagaagtcatctagtatgatccttaaattttacagatgataaatttgagagtccagagaaaat
Target sequence
taatggttgagggatttgtcttttttgctgctcttttgatgtcttctagattgccaatgtttttcctatggaatacttggcagaactgaaaatgcatctaaatgtgatctgaataataaaaagtagaatggatctctcacctcctttaatatacaagccatacttcttttattatgtttttgttttttaattatactttaagttctgggatacatgtgcagaatgtgcaggtttgtaacataggtatacacatgc
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
Curate