Basic Information
VIS ID
TVIS10020174
Fusion event
HBV-chr10 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1162
End
2258
Orient
+
Integrated sequence
GGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGT
Host Sequence
Chromosome
chr10
Cytoband
q26.3
Reference genome
GRCh37/hg19
Start
132646551/130848288 (Hg38)
End
132647599/130849336 (Hg38)
Orient
+
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Nearest miRNA
hsa-mir-107/Upstream/1004914; hsa-mir-202/Downstream/113252;
Nearest TSS
ENST00000439456/Upstream/409221; ENST00000436942/Downstream/245882;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/62388, chr10-CpG: 20/Downstream/226057
Upstream sequence
ggtagttgtattacctctcacttccaggtaaaggaaaaaagcctccaaaaagttaaataactcatcctaggacatacagctaagaaaagaaaggacagga
Downstream sequence
atcattctcaaattttttaaaaccaaagtcaaagagaaaaatctttaaaatagccagagggggaaattgggtcactaccttcagagcagcaaagctgaca
Target sequence
ggtctacttgatgtggatcagagtcccagaaaaagcaaggggggtggggtgagactggagcagcctttgagaaaatgttcatggaagatttccccaaattgCtggattcatctgctcaggctgccaaaacaaaacaccaccgtttgggcttaaacaacagaagtttattttcttttctttattcttattatacttttagttctgggatatgtgtgcagaatgtgcaggtatgttatataggtatacacatgccat
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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