Basic Information
VIS ID
TVIS10020176
Fusion event
HBV-chr22 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1156
End
2252
Orient
+
Integrated sequence
GGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCG
Host Sequence
Chromosome
chr22
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
34992430/34596438 (Hg38)
End
34993478/34597486 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-1286/Upstream/1159769; hsa-let-7a-3/Downstream/738154;
Nearest TSS
ENST00000624155/Upstream/387176; ENST00000624442/Downstream/43693;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/673789, chr22-CpG: 76/Downstream/659882
Nearby gene
LOC441996(-5153) ;
Upstream sequence
AATCTGGTCAGTAGCCATAGCCTACCATTGATAGTACAAATGCACATTATCCCCAGATATGAGCCTGTTCGTCACTGTAGCCTTAGGACATGGCAATTGC
Downstream sequence
TTTGGCAGCAAAGCAACTTGACTCTCTTAATTGTGCTTTGCTTCATCTTGAATTAAAATAATTACATTGAATTCTGTGACAAACAATAGAATGCTAGTAG
Target sequence
ACACACTGGCACATGAGTTCTTCTGTGCGGAATTGGGCATGTGGCTGAACCTAAGCTGGGGATAACCCATTCTGCACACTCAGACTGGAGATCGCCTCCTGGCTCCCTTCTGTCCTAGTACTGCTCATATATCTGGTTTCTTGCTCTCTCAGAGCCATGGGCACCCCAGAACTCTGCCACCTTTTTCTTTCTTCTGTCCCATGGACTCTCCGGGAACAGAGGGCTCAGGAATAAAGCTGACATTTAACTGTAAGT
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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