Basic Information
VIS ID
TVIS10020181
Fusion event
HBV-chr10 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
822
End
1922
Orient
+
Integrated sequence
GGTATACATTTGAACCCTAATAAAACCAAACGTTGGGGCTACTCCCTTAACTTCATGGGATATGTAATTGGAAGTTGGGGTACTTTACCGCAGGAACATATTGTACAAAAACTCAAGCAATGTTTTCGAAAATTGCCTGTAAATAGACCTATTGATTGGAAAGTATGTCAAAGAATTGTGGGTCTTTTGGGCTTTGCTGCCCCTTTTACACAATGTGGCTATCCTGCCTTGATGCCTTTATATGCATGTATACAA
Host Sequence
Chromosome
chr10
Cytoband
q26.2
Reference genome
GRCh37/hg19
Start
129390981/127592717 (Hg38)
End
129392031/127593767 (Hg38)
Orient
+
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Nearest miRNA
hsa-mir-107/Upstream/1772895; hsa-mir-202/Downstream/2249532;
Nearest TSS
ENST00000439456/Upstream/43348; ENST00000388920/Downstream/143468;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/195415, chr10-CpG: 242/Downstream/142379
Upstream sequence
ctgtaatcccagctctttgggaggctgaggagggcggaacaaaatgtcaggagttggagaccagcctgcccaatatggtgaaaccccgtctctactgaaa
Downstream sequence
GAGATTTACAGCTCTGAACCTTCAGTAGAAATTTGTGGAGCAAACTCTAACCAAACTTTGCAATATCAAATTTTTACAATGTTAGTATAAATAAAAAGAA
Target sequence
GGTTAAGTCTGGAAGCAATCACTGTctgttgctgctgctgctcctgctgctgACAGGTCTAGAGGAGGTAGGTGTCTAATCATTGTGAAGTGGAGACAGCCCTTCCCCGTGCGACACCAGGAAAGAGTCTAAATTGCCCTGTTCTCCACAAGCCATTTTCATTAGATAGATGTCTAATTCTCCTAGTGGGCACGTGGCCCTGGCGGTCTTATAAAGCCCAGGGTGTGCAGACAGAGTTCCCCCAGTGAGACTCTA
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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