Basic Information
VIS ID
TVIS10020182
Fusion event
HBV-chr6 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1158
End
2258
Orient
+
Integrated sequence
CAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGG
Host Sequence
Chromosome
chr6
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
48434140/48466404 (Hg38)
End
48435190/48467454 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-10398/Upstream/3268634; hsa-mir-10524/Downstream/3676895;
Nearest TSS
ENST00000381078/Upstream/397715; ENST00000335783/Downstream/995737;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/397510, chr6-CpG: 20/Downstream/995767
Upstream sequence
CAAATGGCAATATCTTTTACCAAAGTGGCACGGCTCAAAACCGCAGGCGTCCAAAGGTGAAGGTGTACATGCATTTGATCCTTCTTTCTGTTATCACCTT
Downstream sequence
taaaatggtttatgtccagaagaccaacaataacaaatgctggcaaagatatggagaaaagggaacactcacacactgttggtgggaatgtaaattagta
Target sequence
GAATCTAGGTGTAGTCAGGCCCCATTAGCTCTCTAAAAACCTGCATCCAATGGGCACTTCTGTGAAAGTGAGACACTCAATGTTTTCAACTCCTTTATGTGTCTGAGCTGAAAGGAATTGTGAATGCATTTTATCTTCACAAAAGCAAGTGGTGAAAAATCTAAATAccctatcaaaataccaatggcattctttacagaaatagaaaaaacagtttccaaaatttaaatggaagtacaaaagacccggaatggc
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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