VISDB Viral Integration Site DataBase

VIS ID

TVIS10020186

Fusion event

HBV-TEAD1 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1177

End

2277

Orient

+

Integrated sequence

AAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCC

Chromosome

chr11

Cytoband

p15.3

Reference genome

Start

End

12711709/12690162 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-98-5p ; hsa-mir-320a ; hsa-mir-215-3p ; hsa-mir-503-3p ; hsa-mir-548at-5p ; hsa-mir-873-5p ; hsa-mir-101-5p ; hsa-mir-377-3p ; hsa-mir-1324 ; hsa-mir-5004-3p ; hsa-mir-1261 ; hsa-mir-4748 ; hsa-mir-4464 ; hsa-mir-624-3p ; hsa-mir-548e-5p ; hsa-mir-7150 ; hsa-mir-580-3p ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-4736 ; hsa-mir-4763-3p ; hsa-mir-1207-5p ; hsa-mir-6077 ; hsa-mir-5580-5p ; hsa-mir-219a-1-3p ; hsa-mir-6868-5p ; hsa-mir-9500 ; hsa-mir-4267 ; hsa-mir-4445-3p ; hsa-mir-4722-5p ; hsa-mir-1286 ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-494-3p ; hsa-mir-548p ; hsa-mir-561-3p ; hsa-mir-5187-3p ; hsa-mir-6515-3p ; hsa-mir-1236-3p ; hsa-mir-3140-5p ; hsa-mir-4713-5p ; hsa-mir-3156-3p ; hsa-mir-2116-3p ; hsa-mir-532-3p ; hsa-mir-150-5p ; hsa-mir-4301 ; hsa-mir-181a-2-3p

Nearest miRNA

hsa-mir-210/Upstream/525345; hsa-let-7a-2/Downstream/3279371;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/13678, chr11-CpG: 198/Downstream/318621

Upstream sequence

gctactaaaaatacaaaaaattagccaggcgtggtggcaggcgcctgttgtcccaggtactcgggtggctgaggcaggagaatggcgtgaacccgggagg

Downstream sequence

acccaggaggcggagcttgtagtgagctgagattgcgccactgcactccaacctgggcgacagagtgagactccgtctcaaaaaaaaaaaaaaaaaaaaa

Target sequence

TCCTCCCTGGAAAACACATCCACCCTTCCTGCCTCCACTTTTCACCCTTTCTCCTCTGCTCTTATCACTTTAAGATCTCAGAGACTCTACCCTGCAGTTCACTACATTTCACCAAAAATGGTCATCAGAAAAGCACCACTTCTGCTCTCTTTAACACTGGATTGAATCTGTTGGCTTATAGAGTTCCCAGCACTCTTGATAGTTGTTACTATTTTGGAATAACATAACTCATTCTCATCCGCATTATGCTTATGA