Basic Information
VIS ID
TVIS10020189
Fusion event
HBV-chr4 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
74
End
1174
Orient
+
Integrated sequence
CCGGAACAGTAAACCCTGTTCCGACTACTGCCTCACCCATATCGTCAATCTTCTCGAGGACTGGGGACCCTGCACCGAACATGGAGAGCACAACATCAGGATTCCTAGGACCCCTGCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCACAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAGCACCCACGTGTCCTGGCCAAAATTCGCAGTCCCCAACCTCCA
Host Sequence
Chromosome
chr4
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
63647266/62781548 (Hg38)
End
63648316/62782598 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-12113/Upstream/1858864; hsa-mir-1243/Downstream/3494226;
Nearest TSS
ENST00000502981/Upstream/615994; ENST00000507857/Downstream/345713;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/1578465, chr4-CpG: 60/Downstream/566531
Upstream sequence
tgtgtgtaaagctacccccaaacctagtggtattatataaaaattattgtattatgctaagagattctggcctcattaatgtatgcttttattccatgac
Downstream sequence
CTTTTGTTTGCAAGGATTCCACAGGAAGAGGGAAATTTTATTTCCAAAAAGGGAGACATACAATTAACTTGAGTCCAATAGTAAAAAATCAGTATAATCA
Target sequence
gaagagcacacagCCTTAGTAAATGTGATCAGAAGTATGAGGGGGGAGTACCCACAATTGGACAGTAACCAATTAAGGCACTATCAGTTACACTTGCCAGTCAAATTTTCCACTAATTTAGTTCTCTCCTGTTCTCTCCTTTTGGTATATTTCTTTTGTTTGTATTTTAATTTAAGCATATTTCTCGTAATTATACCTATATTTGTTCCCCTTCTCAAATCTTAGCTTTAATTGGAAACTGTTCTCCCAAAAAGA
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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