Basic Information
VIS ID
TVIS10020190
Fusion event
HBV-chr16 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1
End
905
Orient
+
Integrated sequence
TCCACAACATTCCACCAAGCTCTGCTAGATCCCAGAGTGAGGGGCCTATATTTTCCTGCTGGTGGCTCCAGTTCCGGAACAGTAAACCCTGTTCCGACTACTGCCTCACCCATATCGTCAATCTTCTCGAGGACTGGGGACCCTGCACCGAACATGGAGAGCACAACATCAGGATTCCTAGGACCCCTGCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCACAGAGTCTAGACTCG
Host Sequence
Chromosome
chr16
Cytoband
p12.2
Reference genome
GRCh37/hg19
Start
22743309/22731988 (Hg38)
End
22744359/22733038 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-1225/Upstream/1225853; hsa-mir-11401/Downstream/1470078;
Nearest TSS
ENST00000527434/Upstream/118505; ENST00000473392/Downstream/80163;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/158544, chr16-CpG: 175/Downstream/80257
Upstream sequence
aatcccagcactttgggaggctgaggctggtggatcacttgatgtcaggagtttgagatcagcctggccaacatggtaaaacctcctctctactaaaaat
Downstream sequence
aggtgtcatggGCCTCTGCTGTCAACACAACATGTTCATTATTCAGGCCTCCTTAAGGCAGTCTCTGGTTTCCGTCTGAGGACATAGTTGGGCTATCCCT
Target sequence
gagtctgttggtaagtgtattttaaattctgagaggtattttcagacttctctccaaagaggctgcctcattaccaggaatgtgtatgcctatgacttcacacccttgggatatcttgttctatcaaagtctttgtttttgtcagtctggtgggtgaaatgtacagcttgtcaatgttttagattgcatatctttATAAACAATCATCTTTAAGGGAAGGACAATAAAGTAAGGTTGTGAGAGATTTTGTATTTT
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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