Basic Information
VIS ID
TVIS10020191
Fusion event
HBV-chr16 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1
End
905
Orient
+
Integrated sequence
TCCACAACATTCCACCAAGCTCTGCTAGATCCCAGAGTGAGGGGCCTATATTTTCCTGCTGGTGGCTCCAGTTCCGGAACAGTAAACCCTGTTCCGACTACTGCCTCACCCATATCGTCAATCTTCTCGAGGACTGGGGACCCTGCACCGAACATGGAGAGCACAACATCAGGATTCCTAGGACCCCTGCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCACAGAGTCTAGACTCG
Host Sequence
Chromosome
chr16
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
31401858/31390537 (Hg38)
End
31402908/31391587 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-1225/Upstream/496552; hsa-mir-11401/Downstream/2771991;
Nearest TSS
ENST00000527434/Upstream/19063; ENST00000444228/Downstream/1725;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/18719, chr16-CpG: 86/Downstream/35983
Nearby gene
ITGAX(-7540) ; ITGAD(+2686) ;
Upstream sequence
ttatttttgcaaatattgttgtaatgaccattattctacaatgttaaaaaatactcatgtacgggtttttgttggacaaattcctagaaggagaattgct
Downstream sequence
tatacacctgcctcagcctcccaaagtgctggaattacagacataagccactgtgcccagccAAATGTTTTAAATAATTGTCACATATATATACAAAATA
Target sequence
aataaaaattaattgattaattaattaaaaatttactgagagctggtggttcctttaagggtggagccgccatcaagtccccagaggatgccctgaatttgggGGCATCACCTTCAGCTGCTGTGGACTCTGAGCCTTGGCAGCTCCAGCTCCAGGCCTGGGAGAAAGATGATTTCCTGGCAGCGTgcagtgattgtgagcatttgactaccttactgcattttgcccttatcattgctctccaaacatgagtgg
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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