VISDB Viral Integration Site DataBase

VIS ID

TVIS10020199

Fusion event

HBV-CDK15 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1068

End

2164

Orient

+

Integrated sequence

TGTATACAATCTAAGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATATCTAAACCTTTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTT

Chromosome

chr2

Cytoband

q33.1

Reference genome

Start

End

202709739/201845016 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-574-5p ; hsa-mir-147a ; hsa-mir-6734-5p ; hsa-mir-1226-5p ; hsa-mir-6834-5p ; hsa-mir-6867-5p ; hsa-mir-644a ; hsa-mir-3911 ; hsa-mir-3650 ; hsa-mir-4455 ; hsa-mir-6747-5p ; hsa-mir-6738-5p ; hsa-mir-5194 ; hsa-mir-1914-3p ; hsa-mir-423-5p ; hsa-mir-3184-5p ; hsa-mir-6782-5p ; hsa-mir-876-3p ; hsa-mir-323a-5p

Nearest miRNA

hsa-mir-10b/Upstream/12710857; hsa-mir-1244-1/Downstream/4938218;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/62536, chr2-CpG: 334/Downstream/187647

Upstream sequence

CAGTGGTTGCTGGGATCAGGCCATTGACACCCTCATGTGACTGTAATTAAATGGACTGGTCACCTGACAGTTTTCCATAGTCAGTATAGACCAtgacata

Downstream sequence

tgcatgcctgtaatcccagttactcaggaggctgaggcaggagaatcacttgaacctgggaggtggaggttgcagtgagctgagattgcaccactgcact

Target sequence

AAAAGGCAACAAGCTTCTTCCAGGCAATGGAAGGCTTTTTGGGGGAGAAAAGAAAGTGAATTACAGGTTTAAACCTAGGAATGTCATTTTTTGAAACTTGTTTAAAATATTTTCAATCCTTctagtggtttgtgagctcctggggtttctggaaggtgtttgggaactggatagagggttagttcatgcctttaaaagccaatacatttccatttctcttttataaccaagtaataacccaattatgcatgtatt