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VISDB
Viral Integration Site DataBase
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TVIS10020204
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10020204
Fusion event
HBV-TERT integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
130
End
1226
Orient
+
Integrated sequence
AGGACTGGGGACCCTGCACCGAACATGGAGAGCACAACATCAGGATTCCTAGGACCCCTGCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCACAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAGCACCCACGTGTCCTGGCCAAAATTCGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAACTTGTCCTGGCTATCGCTGGATGTGTCTG
Host Sequence
Chromosome
chr5
Cytoband
p15.33
Reference genome
GRCh37/hg19
Start
1270683/1270568 (Hg38)
End
1271731/1271616 (Hg38)
Orient
+
Location type
Intronic
Target gene
TERT
miRNAs that regulate target gene
hsa-mir-138-5p
;
hsa-mir-498
;
hsa-mir-193b-3p
;
hsa-mir-335-5p
;
hsa-mir-512-5p
;
hsa-mir-1207-5p
;
hsa-mir-1266-5p
;
hsa-mir-1182
;
hsa-mir-181a-5p
;
hsa-mir-6776-3p
;
hsa-mir-197-3p
;
hsa-mir-6740-3p
;
hsa-mir-6760-3p
;
hsa-mir-532-5p
;
hsa-mir-3064-5p
;
hsa-mir-422a
;
hsa-mir-346
;
hsa-mir-1226-3p
;
hsa-mir-1255a
;
hsa-mir-1255b-5p
;
hsa-mir-143-3p
;
hsa-mir-3161
;
hsa-mir-3605-5p
;
hsa-mir-3620-3p
;
hsa-mir-3682-3p
;
hsa-mir-4323
;
hsa-mir-4712-3p
;
hsa-mir-4733-3p
;
hsa-mir-4758-3p
;
hsa-mir-4770
;
hsa-mir-6088
;
hsa-mir-7112-3p
Nearest miRNA
hsa-mir-4635/Upstream/207594; hsa-mir-10397/Downstream/37694;
Nearest TSS
ENST00000502646/Upstream/4044;
ENST00000605200/Downstream/11394;
Nearest CpG islands
chr5-CpG: 26/Target
, None/Upstream, None/Downstream
Nearest cancer related gene
TERT
(OG, No orient, 0)
Upstream sequence
GGgaacctgcagaaaacataaccacagttctagtcctgacgatgcttctgcctggctatgtgatctcaaacaagccacttaacctctctgagccttgttt
Downstream sequence
CCCCTAGAGCCGAGCAAGTGCTAACAGGCATCTGCAAAGAGCCACAGGGCCACGTGGACAGACCACATCTGCAAAGGGCCACAGGGCCACGTGGACAGAC
Target sequence
TGCCCCATGGCCACCACAGGCCCCCCGAGAGGAGCAAACTACACGGTCAACCCCGCACTTTCCAGATGGGAAATCTAGTCACAGAGAGAAGAGCCCGCGCCCTCGCGGGGGTCACACGACAGGGACAGGAATGAGAATCGGATAAAATCCTTTTGTATCGGGAGAGAGAGATACAAGCGTGTGAGAGCCGGGTGTCCAGCGTCAGTAGTAACTTGGAGCTGACAAGCTGCAGGCTCAAACGCTCGGCGCACACCT
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
Sample Information
×
Sample name
TCGA-CC-A3MB-01A-11R-A213-07
Sample type
Tumor
Gender
Female
CpG Island Information
×
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