Basic Information
VIS ID
TVIS10020206
Fusion event
HBV-LOC105371308 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1186
End
2282
Orient
+
Integrated sequence
CTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGC
Host Sequence
Chromosome
chr16
Cytoband
q21
Reference genome
GRCh37/hg19
Start
63433541/63399637 (Hg38)
End
63434589/63400685 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105371308
Nearest miRNA
hsa-mir-1225/Upstream/5627285; hsa-mir-11401/Downstream/3801636;
Nearest TSS
ENST00000527434/Upstream/30793; ENST00000563061/Downstream/217359;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/1362907, chr16-CpG: 19/Downstream/1550093
Upstream sequence
agacaggagaatcacttgaacctgggaggcagaggttgcaatgagctgagattgcaccactgcactccagcctgggcgacagagcaggactccatctcaa
Downstream sequence
CTTGCGGCAAAGCAGATTAAATTGATCAATATGGATGTTGAAGATTTCGGCAGAAAAATTGTTGAGGAACTCAACTTTCAATATATGGCTCAGTGGGATG
Target sequence
atcccctttaaaatcccaatggattttgttttacagataaaaaaaaatcttaacatttatatggcatcccaaaagacatagaatagttaaagcaatcttgaaagagaacaaagcttgaggcacagcattcttgattttaaaatatactgcaaagctatagtaatcaaaagattactggtttaaaacagtatggtactaacataaagacagacatataggtcactgaaacaaaatatagaccccagaaacaaatct
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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