Basic Information
VIS ID
TVIS10020207
Fusion event
HBV-chr2 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1152
End
2248
Orient
+
Integrated sequence
GCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTG
Host Sequence
Chromosome
chr2
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
123857703/123100127 (Hg38)
End
123858751/123101175 (Hg38)
Orient
+
Fragile sites / regions
FRA2S
Nearest miRNA
hsa-mir-1285-2/Upstream/9378759; hsa-mir-10b/Downstream/4322362;
Nearest TSS
ENST00000437798/Upstream/26646; ENST00000423939/Downstream/343270;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/1344177, chr2-CpG: 79/Downstream/923500
Upstream sequence
TTGCTCAGGAAAGTATAGATATGTTTCCCTTGCCCCGAAGAATGAATTTCTACTGTACTCTGTGATTGCATCTCGCAAATGAATCTTTATAGAGGAAGAC
Downstream sequence
AACCGTATTTCCTTCAGGTTAGAATTGGCCATTTTCTacacacacacacacacacacaccacacacTCTCCTTCAGATATATATATAGATATGTGGACTT
Target sequence
cttggatcttgaatctgttcgctttgaaaacatatcggcaccattatctctctaagtttgcaggccttcaaactcagattgaaataacaccattgtctctcctggttctccagcttgcctactgcagaacttgggatgtttcagcctacttaatcatgtgagccaatcctcataataaatctttcCTTCCTCTGCCCACTCTCATATACATTcatatacatacatatatacatacacacacacacacacacagac
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
Curate