Basic Information
VIS ID
TVIS10020209
Fusion event
HBV-chr5 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1164
End
2260
Orient
+
Integrated sequence
TCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCC
Host Sequence
Chromosome
chr5
Cytoband
p15.33
Reference genome
GRCh37/hg19
Start
4075067/4074954 (Hg38)
End
4076115/4076002 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-4277/Upstream/2366086; hsa-mir-10397/Downstream/2751851;
Nearest TSS
ENST00000502646/Upstream/33190; ENST00000503415/Downstream/59680;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/112556, chr5-CpG: 39/Downstream/790202
Upstream sequence
ACTAGTATAGAGTTTATATCTCTTTGGCATTGCCCAAGTTTTGGAGACGTTGAGACTTGTGGCTAAGCACTCACTGTGTTAATAAATTCTAGTTCCTACG
Downstream sequence
catagacctccattacttggtttagctggtaataatcctggacagaggccaaggcaggaggattgcttgagctcaggagttcaagaccagcctgggcaag
Target sequence
gctttatacaccactgttgcagtcctagagtttccggaatatggctctatattacttatatcatgaagttttgtgcttttgtagcttttaggatattaattagtggcttcgtgtttcagcttaagaaaactccctttcagctgtgtctgtaaggcaaatctaatggtataaacttccttaccttttgtttgtctgccaaagtttatatttctctctcattttggaaatacagctttgcagaatgaagtattcttg
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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