VISDB Viral Integration Site DataBase

VIS ID

TVIS10020210

Fusion event

HBV-CCDC33 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1156

End

2252

Orient

+

Integrated sequence

GGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCG

Chromosome

chr15

Cytoband

q24.1

Reference genome

Start

End

74619744/74327403 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-580-3p ; hsa-mir-4735-5p ; hsa-mir-6822-3p

Nearest miRNA

hsa-mir-10393/Upstream/1026376; hsa-mir-11181/Downstream/83954;

Nearest TSS

Nearest CpG islands

None/Target, chr15-CpG: 55/Upstream/80612, chr15-CpG: 66/Downstream/38294

Upstream sequence

CGAGCTCATGATGGTAAGTTCACAAAGTCCAATATAAAATTTCCAGTTTCTCTTCAGCTCAATTGTCTGTCTTAACATTCTCACTTATTTTTCTGTTTCA

Downstream sequence

gcgggcagattacctgaggtcaggagttcgagactagcctgaccaacatggtgaaactccatctctactaaaaagacaaaaattagctgggcgtggtggt

Target sequence

AGGAAAAAGAGATGCTGTTGCCAGGCACCctgtgtgccagagcctgggctggcactgttcatgccccctctctctccacagcaaccccccttggggtggggtgattttcccattccacggatgaggacgctaaggctcagagaACAGCCTCCCTTCCAGAGCCAAAGCGAAGGTGTCGGTGCAGCAAAGGCCACCAGCGCTCAGTGGCAGTGGGGCAATTCAAACCCAAGGACACCTGACATTTCTCACCTGGGC