VISDB Viral Integration Site DataBase

VIS ID

TVIS10020211

Fusion event

HBV-MPRIP integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

987

End

2083

Orient

+

Integrated sequence

TGTCAAAGAATTGTGGGTCTTTTGGGCTTTGCTGCCCCTTTTACACAATGTGGCTATCCTGCCTTGATGCCTTTATATGCATGTATACAATCTAAGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATATCTAAACCTTTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGA

Chromosome

chr17

Cytoband

p11.2

Reference genome

Start

End

17039687/17136373 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-31-5p ; hsa-mir-124-3p ; hsa-mir-1-3p ; hsa-mir-1909-3p ; hsa-mir-1296-5p ; hsa-mir-324-3p ; hsa-mir-542-5p ; hsa-mir-2113 ; hsa-mir-1290 ; hsa-mir-4450 ; hsa-mir-4696 ; hsa-mir-218-5p ; hsa-mir-568 ; hsa-mir-595 ; hsa-mir-636 ; hsa-mir-643 ; hsa-mir-648 ; hsa-mir-1252-5p ; hsa-mir-3185 ; hsa-mir-4271 ; hsa-mir-4533 ; hsa-mir-4725-3p ; hsa-mir-4747-5p ; hsa-mir-5196-5p ; hsa-mir-6783-5p ; hsa-mir-6780b-5p ; hsa-mir-3120-3p ; hsa-mir-3942-5p ; hsa-mir-4703-5p ; hsa-mir-183-5p ; hsa-mir-593-5p ; hsa-mir-4786-3p ; hsa-mir-8076 ; hsa-mir-549a ; hsa-mir-3529-3p ; hsa-mir-5010-3p ; hsa-mir-128-2-5p ; hsa-mir-128-1-5p ; hsa-mir-6781-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-495-3p ; hsa-mir-5688 ; hsa-mir-548m ; hsa-mir-5011-3p ; hsa-mir-6877-5p ; hsa-mir-6845-3p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-2681-5p ; hsa-mir-27b-3p ; hsa-mir-27a-3p ; hsa-mir-4328 ; hsa-mir-3681-3p ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-3160-5p ; hsa-mir-3691-3p ; hsa-mir-6814-5p ; hsa-mir-7977 ; hsa-mir-4530 ; hsa-mir-646 ; hsa-mir-3613-3p ; hsa-mir-122-5p ; hsa-mir-3135b ; hsa-mir-3136-5p ; hsa-mir-3652 ; hsa-mir-4430 ; hsa-mir-4439 ; hsa-mir-4462 ; hsa-mir-4513 ; hsa-mir-504-3p ; hsa-mir-5190 ; hsa-mir-5698 ; hsa-mir-6855-3p ; hsa-mir-6857-3p ; hsa-mir-7156-3p

Nearest miRNA

hsa-mir-1253/Upstream/853237; hsa-mir-10226/Downstream/677107;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/92218, chr17-CpG: 20/Downstream/22257

Upstream sequence

TCTCCTCGGAGCGAAGGTGGCAGCCCCCATGTCCCCGTCCCCGCTTGGCCCTGCCACCTGCCTGCCCTACCTTGGCAAGGTGCTTGGCGATGCCACGCCC

Downstream sequence

TCCAGCTCAGAGTCCCAGCCAGAGCCAGCCTCCTGCTGCCAGCTCCCTGCGGGAACCTGGGCTAGAGAGCAAAGAAGGTGAGCGGAGGCCAGGCTGGCTT

Target sequence

CACCTTTTCCATCTGGGCTACTGGCTTGTATCTAGCTTtgtgtgtgagcttgtgagtgtgagagagcaagcatgtgcacatgaatgtgtatatgcatttgtgagtgtgtgcctgtgtgCAGATTCAAGTGGGGTATTTGGtgtctttgtgtgttctgtctgctataataaaataccacaggctagtcagcttataaataatagaaatttttctcacagcaggctggttagtccaagattaaagtgctagtatttt