Basic Information
VIS ID
TVIS10020213
Fusion event
HBV-LOC101927588 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1080
End
2176
Orient
+
Integrated sequence
AAGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATATCTAAACCTTTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGAC
Host Sequence
Chromosome
chr8
Cytoband
q24.13
Reference genome
GRCh37/hg19
Start
125258697/124246456 (Hg38)
End
125259745/124247504 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA8C ; FRA8E
Target gene
LOC101927588
Nearest miRNA
hsa-mir-12123/Upstream/898326; hsa-mir-10400/Downstream/261011;
Nearest TSS
ENST00000518652/Upstream/74934; ENST00000517482/Downstream/24179;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/477431, chr8-CpG: 34/Downstream/53938
Upstream sequence
CTATGTGACCATGAATTCCACAAGGAAAACACCTATTTGTCATCTTACTGAGTGTTTTGGCTTCAGCAACTAGCTGGGAGCTAGATACAGAGGCATCGAT
Downstream sequence
TGGACCCACCTGCAGCCCGGAGCCACCCAATCAATCAAAGGGAGACAGAAAACCGAAAATGCTGCATACGAGTAAAATAAATAATGGCCAATTAGTCACC
Target sequence
aaaaataataaataaataaaaaGATGCTCACAAGACAGGTGAAAAAAAGATCCCAGACCTTTTGGGATAATTCCAAAGTAGATTCTTAGATTATTTTTTCACCCACCTTCCTTTCCAAAATATCTCAACATAAGCTTTCAGGAAATTTCACTGTCTAATAATAACAAAAACAAAAAAATACAGCGGTTTCCATCTATGAAATCCTTACCAGGCACCCAAGCAAAGTGCTTTCCATGGATTATTTGAATCCTTGTT
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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