VISDB Viral Integration Site DataBase

VIS ID

TVIS10020215

Fusion event

HBV-chr17 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1085

End

2181

Orient

+

Integrated sequence

GGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATATCTAAACCTTTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTC

Chromosome

chr17

Cytoband

p11.2

Reference genome

Start

End

19468344/19565031 (Hg38)

Orient

+

Location type

Intronic

Target gene

LOC105371578 ; SLC47A1

miRNAs that regulate target gene

hsa-mir-6770-3p ; hsa-mir-4730 ; hsa-mir-939-5p ; hsa-mir-1343-5p ; hsa-mir-3144-5p ; hsa-mir-920 ; hsa-mir-6726-5p ; hsa-mir-5591-5p ; hsa-mir-4300 ; hsa-mir-6787-5p ; hsa-mir-663a ; hsa-mir-1908-5p ; hsa-mir-4467 ; hsa-mir-4749-5p ; hsa-mir-4706 ; hsa-mir-8072 ; hsa-mir-3960 ; hsa-mir-1307-3p ; hsa-mir-6889-5p ; hsa-mir-6777-5p ; hsa-mir-3189-3p ; hsa-mir-212-5p ; hsa-mir-6784-5p ; hsa-mir-4655-5p ; hsa-mir-4665-5p ; hsa-mir-5010-5p ; hsa-mir-1275 ; hsa-mir-4525 ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-625-5p ; hsa-mir-6883-5p ; hsa-mir-6825-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-3616-3p ; hsa-mir-4680-5p ; hsa-mir-7155-5p ; hsa-mir-637 ; hsa-mir-4700-5p ; hsa-mir-8089 ; hsa-mir-4667-5p ; hsa-mir-330-5p ; hsa-mir-326 ; hsa-mir-181d-3p ; hsa-mir-514a-5p ; hsa-mir-5008-5p ; hsa-mir-6851-3p ; hsa-mir-7160-3p

Nearest miRNA

hsa-mir-1180/Upstream/219409; hsa-mir-10226/Downstream/7728879;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/29604, chr17-CpG: 58/Downstream/14882

Upstream sequence

TTTCTGAAGACTTTGGGCTTGGGGAGAAATGTTAATTTTTTTGTTTGGATTTAGATTCCGTTGTGCTGGTATATTATTTCTTATTCCTAgtctgtgtaca

Downstream sequence

CTTATTTAGTAATTAAACAAGTATTTATTGGGAGACAGTCTTCTAGGTTCTAGTTTAGAGTGACAAAACTCACTCCAAGGGTGTTGTGAATTTCCTGCTT

Target sequence

gtctcagacaaaaaaaaaatgttattagacagaatttagcagcacattgaaaagAATATATTTGGGTGAAATATAAAAGTGAATATAggccaggcgcggtggctcatgcctgtaatcccaacactttgggagactgaggcaaaaggatcacttgagcccaggagttcaagaccagcctgggaaacatggcgaaaccccatctctacaaaaaataaaatttagctgggcatggtggtgtgcacctgtagtcctagc