VISDB Viral Integration Site DataBase

VIS ID

TVIS10020216

Fusion event

HBV-chr17 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1

End

915

Orient

+

Integrated sequence

TCCACAACATTCCACCAAGCTCTGCTAGATCCCAGAGTGAGGGGCCTATATTTTCCTGCTGGTGGCTCCAGTTCCGGAACAGTAAACCCTGTTCCGACTACTGCCTCACCCATATCGTCAATCTTCTCGAGGACTGGGGACCCTGCACCGAACATGGAGAGCACAACATCAGGATTCCTAGGACCCCTGCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCACAGAGTCTAGACTCG

Chromosome

chr17

Cytoband

p11.2

Reference genome

Start

End

19468344/19565031 (Hg38)

Orient

+

Location type

Intronic

Target gene

LOC105371578 ; SLC47A1

miRNAs that regulate target gene

hsa-mir-6770-3p ; hsa-mir-4730 ; hsa-mir-939-5p ; hsa-mir-1343-5p ; hsa-mir-3144-5p ; hsa-mir-920 ; hsa-mir-6726-5p ; hsa-mir-5591-5p ; hsa-mir-4300 ; hsa-mir-6787-5p ; hsa-mir-663a ; hsa-mir-1908-5p ; hsa-mir-4467 ; hsa-mir-4749-5p ; hsa-mir-4706 ; hsa-mir-8072 ; hsa-mir-3960 ; hsa-mir-1307-3p ; hsa-mir-6889-5p ; hsa-mir-6777-5p ; hsa-mir-3189-3p ; hsa-mir-212-5p ; hsa-mir-6784-5p ; hsa-mir-4655-5p ; hsa-mir-4665-5p ; hsa-mir-5010-5p ; hsa-mir-1275 ; hsa-mir-4525 ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-625-5p ; hsa-mir-6883-5p ; hsa-mir-6825-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-3616-3p ; hsa-mir-4680-5p ; hsa-mir-7155-5p ; hsa-mir-637 ; hsa-mir-4700-5p ; hsa-mir-8089 ; hsa-mir-4667-5p ; hsa-mir-330-5p ; hsa-mir-326 ; hsa-mir-181d-3p ; hsa-mir-514a-5p ; hsa-mir-5008-5p ; hsa-mir-6851-3p ; hsa-mir-7160-3p

Nearest miRNA

hsa-mir-1180/Upstream/219409; hsa-mir-10226/Downstream/7728879;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/29604, chr17-CpG: 58/Downstream/14882

Upstream sequence

ctcgatctcctgacctcatgatccacccaccttggcctcccaaagtgctgggattacaggcgtgagccaccattcctggcctggagaaataacttgatcc

Downstream sequence

CTTATTTAGTAATTAAACAAGTATTTATTGGGAGACAGTCTTCTAGGTTCTAGTTTAGAGTGACAAAACTCACTCCAAGGGTGTTGTGAATTTCCTGCTT

Target sequence

gtctcagacaaaaaaaaaatgttattagacagaatttagcagcacattgaaaagAATATATTTGGGTGAAATATAAAAGTGAATATAggccaggcgcggtggctcatgcctgtaatcccaacactttgggagactgaggcaaaaggatcacttgagcccaggagttcaagaccagcctgggaaacatggcgaaaccccatctctacaaaaaataaaatttagctgggcatggtggtgtgcacctgtagtcctagc