Basic Information
VIS ID
TVIS10020218
Fusion event
HBV-chr17 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1177
End
2273
Orient
+
Integrated sequence
AAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCC
Host Sequence
Chromosome
chr17
Cytoband
p13.1
Reference genome
GRCh37/hg19
Start
8566663/8663345 (Hg38)
End
8567711/8664393 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-1253/Upstream/476341; hsa-mir-10226/Downstream/3417506;
Nearest TSS
ENST00000595228/Upstream/32584; ENST00000585297/Downstream/80394;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/31730, chr17-CpG: 46/Downstream/81292
Nearby gene
LOC105371525(+7237) ;
Upstream sequence
acatatgattagggcaattgtaaaatctaaatatggactttggtacaagattattatctaccccatgtaaaatttcctgcttttcataactatgctgtgg
Downstream sequence
ccagcactttgggaggccgaggtgggtggatcacaaggtcaggagatcaagaccagcctggccaacatggtgaaaccctgtctctactaaaaatacaaaa
Target sequence
GAGACAGTTCCAGAGACTGGCCCAGGAAAACAAATTATATATTCCTCCTCATTAAAATGTCTCAGCAAGACCCTTAAATCAGGCTTTGAGGTCCAGGTTCCAACTACTTCTCAGTTAGAATTTCTCCTGGGCGTTTTGGTGGTTCTTGCCAAATTGGGTAGTTCCCAATGTGGGGACTGTTTCTAAATCAGGGTCTGAGAGCAACCAGCCTCCTTAGGAAAACGACGAAAGAAATTCAAATGGAAAAGAAGTATT
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
Curate