Basic Information
VIS ID
TVIS10020219
Fusion event
HBV-chr17 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1112
End
2208
Orient
+
Integrated sequence
GGCCTTTCTGTGTAAACAATATCTAAACCTTTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTC
Host Sequence
Chromosome
chr17
Cytoband
p13.1
Reference genome
GRCh37/hg19
Start
8566634/8663316 (Hg38)
End
8567682/8664364 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-1253/Upstream/476312; hsa-mir-10226/Downstream/3417535;
Nearest TSS
ENST00000595228/Upstream/32555; ENST00000585297/Downstream/80423;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/31701, chr17-CpG: 46/Downstream/81321
Nearby gene
LOC105371525(+7266) ;
Upstream sequence
ATTGTTCCGAATTCATCATTTAGCTTTATATGTACATGCCAGTTAGAGTCAGAATGATGGGAATAAAATGATTTCATTCTGTCTGTATTATTCCCTAGAG
Downstream sequence
gccgggcgtggtggctcatgcctgtaaccccagcactttgggaggccgaggtgggtggatcacaaggtcaggagatcaagaccagcctggccaacatggt
Target sequence
ATCCATTACCTTGATGCCTGTCTTTCAGGGAGACAGTTCCAGAGACTGGCCCAGGAAAACAAATTATATATTCCTCCTCATTAAAATGTCTCAGCAAGACCCTTAAATCAGGCTTTGAGGTCCAGGTTCCAACTACTTCTCAGTTAGAATTTCTCCTGGGCGTTTTGGTGGTTCTTGCCAAATTGGGTAGTTCCCAATGTGGGGACTGTTTCTAAATCAGGGTCTGAGAGCAACCAGCCTCCTTAGGAAAACGAC
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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