Basic Information
VIS ID
TVIS10020221
Fusion event
HBV-chr22 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1812
End
2908
Orient
+
Integrated sequence
CATGCAACTTTTTCCCCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGAGCTTCTGTGGAGTTACTCTCTTTTTTGCCTTCTGACTTCTTTCCTTCTATTCGAGATCTCCTCGACACCGCCTCTGCTCTGTATCGGGAGGCCTTAGAGTCTCCGGAACATTGTTCACCTCACCATACAGCACTCAG
Host Sequence
Chromosome
chr22
Cytoband
q12.3
Reference genome
End
36634303/36238257 (Hg38)
Orient
+
Fragile sites / regions
Nearest miRNA
hsa-mir-1286/Upstream/900410; hsa-let-7a-3/Downstream/48590;
Upstream sequence
CATTGTTGGCCTGGCTCCCACCTTTGTCTGGAGCCTCTGCTGGGGGTTGAGGCTGGATACTGCCCCTCAGGCTTGACTAGGACACAGTGTGTACTCCATG
Downstream sequence
ATGACATGGCCCAGCTTCAGTTTCACTTTCAGTTGAGAAATTGAAtttaatttttctttctatcttgatgggcatctctttttggtgaagaacaaataag
Target sequence
GGTGAGCCTGCAGGCTGGTCAATTCCGGTGTCCAACTGAGCGACCTGGAAGAGGAGCCCTCCCTCCCACCTCAGCTCTGAGCCAAGCTCTCCAGATGCAGAGGACAGGGACTCTCAGCAAAGCATCTCCCTCCAAGTGGTTGTGGGGCATCCTCCTTGGGCAGGGAAAGAGGAGTCGAAATGATTTCCTGAGAAATCGTCAttttcattttatttttgagaaactgtcttgctctgtcacccagtctggagtgct
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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