Basic Information
VIS ID
TVIS10020222
Fusion event
HBV-chr14 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1180
End
2276
Orient
+
Integrated sequence
TGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGT
Host Sequence
Chromosome
chr14
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
82696004/82229660 (Hg38)
End
82697052/82230708 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-1260a/Upstream/4963370; hsa-mir-1185-1/Downstream/11717518;
Nearest TSS
ENST00000550708/Upstream/486522; ENST00000555798/Downstream/411912;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/695570, chr14-CpG: 45/Downstream/3299442
Upstream sequence
ataatatatatgcacaatttaaaacagtgcctggcacataACtattattaatattaacaaataattatagattttaaaataagttaatttaacaaaattt
Downstream sequence
ATGAAGACTTTTTTTTTTCTTTTCCTGTTTTAGAATATAAGGCAGGATAAAGCACAAAATTCCAGGACTAGGGAAAGAATGCTTTAGAATTTTGTTTTTT
Target sequence
GAATTTTAAGATATGACATAGCTAAATAACCTTAATCAGCGTAAGTTTTATTATGGCTATAGCTATAATTTCATTAAGAAACCTATTTGATCTCTAATGAATCAAACTCAGTAAACTTCAATTTTCCAACTTCAACCAATCTCAGGGTGTATTATCTCCATTTTCCTTGGTAGTGACTTGTTACTGATATTTTAACAGAGCTTTGAACTGTTTAAATGCGTTTGTCATATGCCTCAGAGAGATTTAGTCCCTGAC
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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