Basic Information
VIS ID
TVIS10020225
Fusion event
HBV-chr22 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1
End
902
Orient
+
Integrated sequence
TCCACAACATTCCACCAAGCTCTGCTAGATCCCAGAGTGAGGGGCCTATATTTTCCTGCTGGTGGCTCCAGTTCCGGAACAGTAAACCCTGTTCCGACTACTGCCTCACCCATATCGTCAATCTTCTCGAGGACTGGGGACCCTGCACCGAACATGGAGAGCACAACATCAGGATTCCTAGGACCCCTGCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCACAGAGTCTAGACTCG
Host Sequence
Chromosome
chr22
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
36633255/36237209 (Hg38)
End
36634303/36238257 (Hg38)
Orient
+
Fragile sites / regions
FRA22A
Nearest miRNA
hsa-mir-1286/Upstream/900410; hsa-let-7a-3/Downstream/48590;
Nearest TSS
ENST00000624155/Upstream/32369; ENST00000475519/Downstream/970;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/170846, chr22-CpG: 24/Downstream/84148
Upstream sequence
CATTGTTGGCCTGGCTCCCACCTTTGTCTGGAGCCTCTGCTGGGGGTTGAGGCTGGATACTGCCCCTCAGGCTTGACTAGGACACAGTGTGTACTCCATG
Downstream sequence
ATGACATGGCCCAGCTTCAGTTTCACTTTCAGTTGAGAAATTGAAtttaatttttctttctatcttgatgggcatctctttttggtgaagaacaaataag
Target sequence
GGTGAGCCTGCAGGCTGGTCAATTCCGGTGTCCAACTGAGCGACCTGGAAGAGGAGCCCTCCCTCCCACCTCAGCTCTGAGCCAAGCTCTCCAGATGCAGAGGACAGGGACTCTCAGCAAAGCATCTCCCTCCAAGTGGTTGTGGGGCATCCTCCTTGGGCAGGGAAAGAGGAGTCGAAATGATTTCCTGAGAAATCGTCAttttcattttatttttgagaaactgtcttgctctgtcacccagtctggagtgct
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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