Basic Information
VIS ID
TVIS10020230
Fusion event
HBV-chr18 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1179
End
2275
Orient
+
Integrated sequence
GTGTTTGCTGACGCAACCCCCACGGGTTGGGGCTTGGCCATAGGCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCGAAACTTATCGGAACCGACAACTCAGTTGTCCTCTCTCGGAAATACACCTCCTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCG
Host Sequence
Chromosome
chr18
Cytoband
q23
Reference genome
GRCh37/hg19
Start
78015643/80257760 (Hg38)
End
78016691/80258808 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-1-2/Upstream/7404378;
Nearest TSS
ENST00000575820/Upstream/10214;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/9972, None/Downstream
Upstream sequence
tttctaattttttgaaaaattatattttaataATAGTTGGACTTTTTTACTCACTACCTTTTCTCTTTATTTTAATAGGTCTACAATTCCTTTAAAGGGG
Downstream sequence
agtagtggtggggtagggtttggggtagggttagggttaggggtagggttatggttaggggtagggttacggttgggggtaggggtaagtttaggggtag
Target sequence
actgaagtacagcatcacagggagacaggcctctggataactgcgggtgggcctgacatccacaagaggtggaggagtagagtcttctctaaactcctctggggaaagggagactccctttcccagtctactaagtagcgggtatttttccttgacactgagcctaccactagaccacggtccgcttggcaatgggcgtcttcccagaggctgatgtcaccgctagaccaaggagccctctggtggccctgtccg
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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