Basic Information
VIS ID
TVIS10020244
Fusion event
HBV-chr14 integration
Validated
No
Detection method
VirusScan
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2016
PubMed ID
27339696
Virus Sequence
Virus name
HBV
Reference genome
NC_003977.1
Start
1544
End
2592
Orient
-
Integrated sequence
CTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTAGCATGGAGACCACCGTGAACGCCCACCAGGTCTTGCCCAAGGTCTTACACAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTC
Host Sequence
Chromosome
chr14
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
44565895/44096692 (Hg38)
End
44566943/44097740 (Hg38)
Orient
+
Nearest miRNA
hsa-mir-208a/Upstream/7144301; hsa-mir-1185-1/Downstream/3663255;
Nearest TSS
ENST00000550708/Upstream/1684119; ENST00000557465/Downstream/286805;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/2489566, chr14-CpG: 22/Downstream/789729
Upstream sequence
ACTAAAAATATAGGAATAAAGTAAAGGCAATGGCTTCataaaatttaaataaaatattttaaaatatctattaaaattaaagataaaattCTGTAATTTA
Downstream sequence
AGCCTAACTCAACATTGCCAACTCTATGAATTCATTTTCTACCTTCTTAGGTCAAATTGATTTCTATCCCCAGTATTATCAAAGAGTAGTATTTATTTAC
Target sequence
CATTCCTTTTGGATCATTTATCCCCACAATAAGAAAATATTCCATTCTTGACAAAATTTAAAAAATGGAAAGACATTCTGTGAACACTTTGAATTTATCATCAATGTCAGGAattgtcacctcctattttgagtttagttactcctcatttcttacctggattaccacaaatgtccccttttcatttccctgtgtcttgacctttttcccttcttatttattcatcacatgttcgagtgttatttctaaagaact
Reference
Cao, S., et al.Divergent viral presentation among human tumors and adjacent normal tissues. Sci Rep,2016, 6: 28294.
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