VISDB Viral Integration Site DataBase

VIS ID

TVIS10020245

Fusion event

HBV-WRAP53 integration

Validated

No

Detection method

VirusScan

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1819

End

2915

Orient

+

Integrated sequence

CTTTTTCCCCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGAGCTTCTGTGGAGTTACTCTCTTTTTTGCCTTCTGACTTCTTTCCTTCTATTCGAGATCTCCTCGACACCGCCTCTGCTCTGTATCGGGAGGCCTTAGAGTCTCCGGAACATTGTTCACCTCACCATACAGCACTCAGGCAAGCT

Chromosome

chr17

Cytoband

p13.1

Reference genome

Start

End

7593037/7689719 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-455-3p ; hsa-mir-106b-3p

Nearest miRNA

hsa-mir-1253/Upstream/465292; hsa-mir-10226/Downstream/398337;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/150, chr17-CpG: 69/Downstream/15138

Upstream sequence

AAGGATAATTCTGCAGAATATATCTATGGCCTTTACCAACCTTCGTTCCATAGAGGGAACTTAATTTTTACTCTGTAGTGCTTCACTGAGGCTTACTAGG

Target sequence

ggaGACAGGTCTGAAGCCTGGAGAATGAGATGCAGAAGAGGTGCAAGACCTGCTGCGCCCTCTGCAGGCGGCGGGGGGGCGGTGCAGGTGCTTTAAGAATTACCGCGGGACTCGGTAGGGGGAGCGTAGGCGCTTCTCGCCAAGATAGAAGCGTTCAGACTACAACTCCCAGCAGCCACGAGGAGCCCTAGGGCTTGATGGGAACGGGAAACCTTCTAACCTTTCACGTCCCGGCTCCGCGGGTTCCGTGGGTCG